Cathine
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Clinical data | |
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Other names |
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Routes of administration | Oral |
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ATC code | |
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Legal status |
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Pharmacokinetic data | |
Elimination half-life | 1.8–8.6 hours[2] |
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Solubility in water | 20 mg/mL (20 °C) |
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D-norpseudoephedrine, also known as cathine and (+)-norpseudoephedrine, is a
Pharmacology
Like amphetamines, cathinone and ephedrine, cathine acts as a norepinephrine releasing agent (NRA).[3] It also acts as a dopamine releasing agent (DRA).[3][4]
Chemistry
Cathine is one of the four stereoisomers of phenylpropanolamine (PPA).
Regulation
The
In Australia, Cathine is officially a schedule 4 drug prescription only, but is not available or approved for any medical use.
In Hong Kong, cathine is regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. Unlawful possession is punishable by severe fines and imprisonment.
Pregnancy
A small study of 642 participants in Yemen found that among pregnant women who chewed khat (containing D-norpseudoephedrine) there was no increased risk of
See also
- L-Norpseudoephedrine, the enantiomer
- Methcathinone
- Ephedra sinica ("Ephedra")
- Ephedrine
- Pseudoephedrine
- Methamphetamine
References
- ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
- PMID 12848785.
- ^ PMID 20553832.
- PMID 33177980.
- ^ "List of psychotropic substances under international control" (PDF). International Narcotics Control Board. Archived from the original (PDF) on 2012-08-31.
- ^ "Scheduling Actions" (PDF). Diversion Control Division. U.S. Department Of Justice, Drug Enforcement Administration (DEA).
- PMID 30601144.
- PMID 28531823.
- PMID 3695559.
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Antiallergic agents, excluding corticosteroids |
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Corticosteroids |
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Other nasal preparations |
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Combination products |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
antagonists
receptor agonists
- Beloranib§
- Bimagrumab§
- Desiccated thyroid‡
- Metformin
- Metreleptin
- Naltrexone
- Setmelanotide
- Topiramate
- ZGN-1061
- Zonisamide
- Water
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Phenethylamines |
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Amphetamines |
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Phentermines |
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Cathinones |
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Phenylisobutylamines | |
Phenylalkylpyrrolidines | |
Catecholamines (and close relatives) |
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Miscellaneous |
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