Chapare mammarenavirus

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Chapare mammarenavirus
electron microscope image of Chapare virus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum:
Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Arenaviridae
Genus: Mammarenavirus
Species:
Chapare mammarenavirus
Synonyms[1]

Chapare virus

Chapare hemorrhagic fever
SpecialtyVirology

Chapare mammarenavirus or Chapare virus is a virus from the family

zoonotic mammarenavirus infection occurred in the village of Samuzabeti, Chapare Province, Bolivia, in January 2003. A small number of people were infected and one person died.[2][3][4]

In 2019, nine people became infected with the virus in the

Virology

The Chapare virus is an enveloped virus with a bi-segmented single-stranded ambisense

Symptoms

After an incubation period of around 9–19 days, initial symptoms include fever, malaise, headache, myalgia, back pain, dizziness, nausea, vomiting and diarrhoea. The disease often progresses to include hemorrhagic and neurological symptoms, such as gingival hemorrhage, anaemia, leukopaenia, confusion, seizures, ecchymoses, bleeding from mucous membranes, hemorrhagic shock and multi-organ failure.[2][5]

Chapare virus RNA was detected in the blood, urine, conjunctiva, semen and in broncho-alveolar and nasopharyngeal samples of the infected patients. Those who survived often had prolonged residual neurological symptoms. Viral RNA was detected in survivors up to 170 days after infection and infectious Chapare virus was obtained in a semen sample of one patient 86 days after symptom onset.[5]

Treatment

Treatment relies mostly on supportive care and early diagnosis. Specific antiviral therapy for Chapare virus infection has yet to be properly investigated.[5]

References

  1. ^ Buchmeier, Michael J.; et al. (2 July 2014). "Rename one (1) genus and twenty-five (25) species in the family Arenaviridae" (PDF). International Committee on Taxonomy of Viruses (ICTV). Retrieved 14 June 2019. in the family Arenaviridae change the name of genus Arenavirus to Mammarenavirus and convert the names of its constituent species to a binomial format, by appending the name Mammarenavirus to each existing name
  2. ^
    PMID 18421377
    .
  3. ^ "New kind of killer virus discovered in Bolivia". NewScientist. New Scientist. Retrieved 2008-04-17.
  4. ^ "Evidence shows human transmission in deadly outbreak of mysterious disease in Bolivia". EurekAlert!. The American Society of Tropical Medicine and Hygiene. 16 November 2020. Retrieved 17 November 2020.
  5. ^
    PMID 35704480
    .
  6. ^ "Researchers confirm human-to-human transmission of rare virus in Bolivia". the Guardian. 2020-11-16. Retrieved 2020-11-17.

External links