Chi-Huey Wong

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Chi-Huey Wong
翁啟惠
President of the Academia Sinica
In office
19 October 2006 – 10 May 2016
DeputyChen Chien-jen, Wang Fan-sen, etc.
Preceded byYuan T. Lee
Succeeded byWang Fan-sen (acting)
Personal details
Born (1948-08-03) August 3, 1948 (age 75)
Yizhu, Tainan County, Taiwan (now Chiayi County)
NationalityTaiwanese
American
Alma mater
The Scripps Research Institute
  • Academia Sinica (Taiwan)
  • National Taiwan University
  • Doctoral studentsCarlos F. Barbas III
    Political partyIndependent

    Chi-Huey Wong (

    Scripps Research Institute,[1] California in the department of chemistry. He is a member of the United States National Academy of Sciences, as awarded the 2014 Wolf Prize in Chemistry and 2015 RSC Robert Robinson Award.[2] Wong is also the holder of more than 100 patents and publisher of 700 more scholarly academic research papers under his name.[3]

    Education

    Wong  received his BS and MS in Biochemical Sciences from National Taiwan University in Taipei, followed by his PhD in chemistry in 1982 at the Massachusetts Institute of Technology under the direction of Professor George M. Whitesides to study the use of enzymes as catalysts in organic synthesis.[4]

    Research and career

    Wong continued his postdoctoral research work with George M. Whitesides at Harvard University from 1982 to 1983, then began his independent career at Texas A&M University in the chemistry department. During his tenure at Texas A&M University, he went through the ranks including assistant professor, associate professor, and professor of chemistry.

    Wong was appointed as the

    Frontier Research Program on Glycotechnology at Riken in Japan[5] and director of the Genomics Research Center at Academia Sinica,[6] and was later appointed by the President of the Republic of China (Taiwan) as the President of Academia Sinica. Now, he is  serving at the Scripps Research Institute as Scripps Family Chair Professor of Chemistry.[7]

    Wong is best known for his original contributions to glycoscience, especially his development of

    In 2016, there was a media report, speculating that he was possibly involved in an insider trading scandal related to a biotech company OBI Pharma, Inc. headquartered in Taiwan, because his adult daughter had held shares in OBI Pharma.[39] When the allegations surfaced in March 2016, Wong was in the United States. He was quite disappointed by the false report and attempted to resign his position as president of the Academia Sinica twice. Both requests were rejected by the president of Taiwan, Ma Ying-jeou. After further consideration, Ma chose to approve Wong's resignation on 10 May.[40] In February 2018, the Shilin District Prosecutors Office announced that charges of insider trading against Wong had been dropped, though an investigation into a possible failure in disclosing his assets during tech transfer of his invention had not yet concluded by the Control Yuan.[41] In April 2022, the Control Yuan publicly announced that Wong did not violate any rule.[42]

    Awards and honors

    Memberships

    Wong was elected as a member of the

    United States National Academy of Sciences in 2002, the World Academy of Sciences in 2007, the United States National Academy of Inventors in 2014, and also an Associate Member of the European Molecular Biology Organization in 2010.[49]

    Bibliography

    Patents

    Wong obtained many patents for his inventions. His representative patents include Globo-H and related anti-cancer vaccines with novel glycolipid adjuvants (US9,603,913B2), Glycan arrays on PTFE-like aluminum coated glass slides and related methods (US8,680,020), Methods and compositions for immunization against virus (US8.741,311), Large scale enzymatic synthesis of oligosaccharides (US9,340,812), Methods for modifying human antibodies by glycan engineering (US10, 087,236), Compositions and methods relating to universal glycoforms for enhanced antibody efficacy (US10,023892), Crystal structure of bifunctional transglycosylase PBP1b from E. Coli and inhibitors thereof (US9890111B2),[50] Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants (US-8906832-B2),[51] Antibiotic compositions and related screening methods (US8916540B2),[52] Hirsutella Sinensis mycelia compositions and methods for treating sepsis and related inflammatory responses (US8486914B2),[53] and Tailored glycoproteomic methods for the sequencing, mapping and identification of cellular glycoproteins (US7943330B2).[54]

    References

    1. ^ "Chi-Huey Wong | Scripps Research". www.scripps.edu. Retrieved 2019-10-14.
    2. ^ "RSC Robert Robinson Award 2015 Winner". www.rsc.org. Retrieved 2019-10-14.
    3. ^ "Chi-Huey Wong – Google Scholar Citations". scholar.google.com.tw. Retrieved 2019-10-14.
    4. ^ "Dr. Chi-Huey Wong's Personal Webpage". www.genomics.sinica.edu.tw. Archived from the original on 2016-04-04. Retrieved 2019-10-14.
    5. ^ "Third RIKEN-Academia Sinica Joint Conference | RIKEN". www.riken.jp. Retrieved 2019-10-23.
    6. ^ "Dr. Chi-Huey Wong's Personal Webpage". www.genomics.sinica.edu.tw. Archived from the original on 2016-04-04. Retrieved 2019-10-23.
    7. ^ "70th Birthday: Chi-Huey Wong :: ChemViews Magazine :: ChemistryViews". www.chemistryviews.org. 3 August 2018. Retrieved 2019-10-23.
    8. PMID 2658059
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    39. ^ Loa, Lok-sin (31 March 2016). "Wong Chi-huey offers resignation". Taipei Times. Retrieved 25 April 2016.
    40. ^ Normile, Dennis (11 May 2016). "Head of Taiwan's Academia Sinica resigns". Science Magazine. Retrieved 21 February 2018.
    41. ^ Kao, Evelyn; Hsiao, Po-wen (21 February 2018). "Insider trading charges dropped against ex-Academia Sinica head". Central News Agency. Retrieved 22 February 2018.
    42. ^ Lin, Liang-sheng; Chung, Jake (12 April 2022). "Wong Chi-huey deserves retrial, Control Yuan says". Taipei Times. Retrieved 12 April 2022.
    43. ^ "Cotten Medal".
    44. ^ "Academia Sinica President Chi-Huey Wong To Receive 2012 Arthur C. Cope Award". Asian Scientist Magazine. 2011-09-08. Retrieved 2019-10-23.
    45. ^ Wolf Prize in Chemistry 2014
    46. ^ "Academia Sinica President Chi-Huey Wong Receives 2015 Robert Robinson Award". www.genomics.sinica.edu.tw. Archived from the original on 2015-05-12. Retrieved 2019-10-23.
    47. ^ Welch Award in Chemistry 2021
    48. ^ Wu, Hsin-yun; Shih, Hsiu-chuan (12 April 2022). "Taiwanese biochemist Wong Chi-huey receives Chemical Pioneer Award". Central News Agency. Retrieved 13 April 2022. Republished as: "Biochemist receives US 'Pioneer' award". Taipei Times. 13 April 2022. Retrieved 13 April 2022.
    49. ^ "EMBO recognizes 63 researchers for advances in life sciences". EMBO. Archived from the original on 2019-05-13. Retrieved 2019-10-23.
    50. ^ [1], "Crystal structure of bifunctional transglycosylase PBP1b from E. coli and inhibitors thereof", issued 2015-12-04 
    51. ^ "Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants – Dimensions". app.dimensions.ai. Retrieved 2019-10-23.
    52. ^ [2], "Antibiotic compositions and related screening methods", issued 2009-01-15 
    53. ^ [3], "Hirsutella sinensis mycelia compositions and methods for treating sepsis and related inflammatory responses", issued 2010-03-30 
    54. ^ [4], "Tailored glycoproteomic methods for the sequencing, mapping and identification of cellular glycoproteins", issued 2008-03-24 

    External links