Choline dehydrogenase
| Choline dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In
- choline + acceptor betaine aldehyde + reduced acceptor
Thus, the two
reduced acceptor
.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is choline:acceptor 1-oxidoreductase. Other names in common use include choline oxidase, choline-cytochrome c reductase, choline:(acceptor) oxidoreductase, and choline:(acceptor) 1-oxidoreductase. This enzyme participates in glycine, serine and threonine metabolism. It employs one cofactor, PQQ.
References
- Minoru Ameyama; Emiko Shinagawa; Kazunobu Matsushita; Koichi Takimoto; Koji Nakashima; Osao Adachi (1985). "Mammalian choline dehydrogenase is a quinoprotein". Agric. Biol. Chem. 49 (12): 3623–3626. .
- Ebisuzaki K, Williams JN (1955). "Preparation and partial purification of soluble choline dehydrogenase from liver mitochondria". Biochem. J. 60 (4): 644–6. PMID 13249959.
- Gadda G, McAllister-Wilkins EE (2003). "Cloning, Expression, and Purification of Choline Dehydrogenase from the Moderate Halophile Halomonas elongata". Appl. Environ. Microbiol. 69 (4): 2126–32. PMID 12676692.
- Takabe T; Tanaka, Y; Aoki, K; Hibino, T; Jikuya, H; Takano, J; Takabe, T; Takabe, T (2003). "Isolation and functional characterization of N-methyltransferases that catalyze betaine synthesis from glycine in a halotolerant photosynthetic organism Aphanothece halophytica". J. Biol. Chem. 278 (7): 4932–42. PMID 12466265.
