Chris Dobson

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Sir
Chris Dobson
FRS FMedSci FRSC
Dobson in 2014
Born
Christopher Martin Dobson

(1949-10-08)8 October 1949
Rinteln, Lower Saxony, West Germany
Died8 September 2019(2019-09-08) (aged 69)
Sutton, London, England
EducationHereford Cathedral Junior School
Abingdon School
Alma materUniversity of Oxford (MA, DPhil)
Awards
Scientific career
Fields
Institutions
ThesisThe conformation of lysozyme in solution (1975)
Websitewww.ch.cam.ac.uk/person/cmd44

Sir Christopher Martin Dobson

Department of Chemistry at the University of Cambridge, and Master of St John's College, Cambridge.[2]

Early life and education

Dobson was born on 8 October 1949 in Rinteln, Germany, where his father, Arthur Dobson was commissioned as an officer.[1][3] Both Arthur Dobson and Christopher Dobson's mother, Mabel Dobson (née Pollard), were originally from Bradford in Yorkshire and had left school at age 14.[3] Dobson had two older siblings, Graham and Gillian.[3] Due to his father's postings, Dobson also lived in Lagos, Nigeria.[3]

Christopher Dobson was educated at Hereford Cathedral Junior School, and then Abingdon School from 1960 until 1967.[3][4] He completed a Master of Arts and Doctor of Philosophy[5] at the University of Oxford, where he was a student of Keble College, Oxford and Merton College, Oxford.[3]

Research and career

Dobson's research largely focused on

protein misfolding, and its association with medical disorders particularly Alzheimer's disease and Parkinson's disease.[1] By applying chemical and biophysical techniques, Dobson investigated links between protein structure, function, and disease.[6]

He is well known for his serendipitous discovery that ordinary proteins can misfold and aggregate to form amyloid structures.[3]

"A postdoc who left his sample of an unfolded protein in an NMR [nuclear magnetic resonance] spectrometer over a long weekend discovered, on his return, that it had turned into a gel. We were curious about this phenomenon and found that the NMR tube was full of amyloid fibrils that we then thought were associated only with diseases".

— Christopher M. Dobson, [7]

Dobson authored and co-authored over 800 papers and review articles,

Science and Cell, which have been cited over 100,000 times.[9] As of 2019 his H-index is 153.[9]

Dobson held

Fellow of Lady Margaret Hall, Oxford and as a University Lecturer in Chemistry, later receiving promotions to Reader, then Professor of Chemistry in 1996.[1][3]

Dobson moved to the

John Humphrey Plummer Professor of Chemical and Structural Biology. In 2007, he became the Master of St John's College, Cambridge, a post which he held until his death in September 2019.[3][10]

In 2012, Dobson founded the Cambridge Centre for Misfolding Diseases,[3] which is currently based in the Chemistry of Health building at the Department of Chemistry at the University of Cambridge.[10][11]

In 2016, Chris Dobson co-founded Wren Therapeutics, a biotechnology start-up company whose mission is to find new therapeutics for Alzheimer's disease.[12][6][13]

Awards and honours

Dobson was

inorganic paramagnets and the silicaceous components of hydraulic materials. Notable here are analyses of the nature and origin of dynamic properties in molecular solids, and their relationship to structure and reactivity.[16]

Dobson's other accolades include:

Mentorship

Dobson mentored and supervised many notable

PhD students and post-doctoral researchers
, many of whom became renowned experts in their own field. These include:

Personal life

Dobson met his wife, Dr Mary Dobson (née Schove) at Merton College at the University of Oxford.[3] They had two sons, Richard and William.[8][10]

He died on 8 September 2019, from cancer, at Royal Marsden Hospital in Sutton, near Surrey.[8]

References

  1. ^
    doi:10.1093/ww/9780199540884.013.U13819. (Subscription or UK public library membership
    required.)
  2. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad "Chris Dobson – CV". Retrieved 11 September 2019.
  3. ^
    ISSN 0140-0460
    . Retrieved 13 September 2019.
  4. ^ "Chemistry Prizes" (PDF). The Abingdonian.
  5. EThOS uk.bl.ethos.453735. Free access icon
  6. ^
    S2CID 216647586
    . Retrieved 28 March 2023.
  7. ^ "Professor Sir Chris Dobson obituary". The Times. 12 September 2019.
  8. ^ a b c d "Professor Sir Christopher Dobson, master of St John's College, Cambridge, dies at 69". Cambridge Independent. 9 September 2019. Retrieved 9 September 2019.
  9. ^ a b Chris Dobson's publications indexed by the Scopus bibliographic database. (subscription required)
  10. ^ a b c "Tributes paid to Master of St John's College who has died age 69". St John's College Cambridge. Retrieved 9 September 2019.
  11. ^ "New research facility for neurodegenerative disorders opened in Cambridge". University of Cambridge. 21 September 2018. Retrieved 9 September 2019.
  12. ^ a b "Knighthood for Prof Christopher Dobson, master of St John's College, in recognition of ground-breaking Alzheimer's research". Cambridge Independent. 8 June 2018. Retrieved 9 September 2019.
  13. ^ "Cambridge spinout grabs $23M round to launch a new campaign to tackle protein misfolding". Endpoints News. Retrieved 9 September 2019.
  14. ^ "Knighthood for eminent scientist Sir Christopher Dobson". Lady Margaret Hall. Retrieved 9 September 2019.
  15. ^ a b Anon (1996). "Sir Christopher Dobson FMedSci FRS". royalsociety.org. London: Royal Society. One or more of the preceding sentences incorporates text from the royalsociety.org website where:

    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived 11 November 2016)
  16. ^ "EC/1996/06: Dobson, Christopher Martin". London: The Royal Society. Archived from the original on 5 March 2017. Retrieved 30 September 2014.
  17. ^ "Bijvoet Medal". Bijvoet Center for Biomolecular Research. Archived from the original on 12 September 2017. Retrieved 12 September 2017.
  18. ^ "Master receives Honorary Degree from King's College London | StJohns".
  19. ^ "Fellows & Scholars : Trinity College Dublin, the University of Dublin, Ireland".
  20. ^ "2013 NAS Members and Foreign Associates Elected".
  21. ^ "Christopher M. Dobson – KNAW". Archived from the original on 3 March 2016. Retrieved 26 June 2014.
  22. ^ "Feltrinelli International Prize awarded to Chris Dobson | Department of Chemistry".
  23. ^ "Election of New Members at the 2018 Spring Meeting | American Philosophical Society".
  24. ^ "Paying tribute to Chris Dobson". www.rsc.org. Retrieved 16 September 2019.
  25. ^ "Membership to Royal Society". Retrieved 27 September 2019.
  26. ^ Cait MacPhee [@sciorama] (13 September 2019). "Chris Dobson was a vocal and practical advocate of women in science before it was cool. The number of women he employed or appointed in Oxford led to us being called "Dobettes" (yes, we knew what you called us, you pricks)" (Tweet). Retrieved 27 September 2019 – via Twitter.
  27. ^ "Membership to Royal Society of Chemistry". Retrieved 6 October 2019.
  28. ^ "Membership to the National Academy of Sciences of the US".
  29. ^ "Membership to Academia Europaea". Retrieved 27 September 2019.
  30. ^ "Citation metrics at Scopus". Retrieved 27 September 2019.
  31. ^ "Membership to Academia Europaea". Retrieved 6 October 2019.
  32. ^ "Citation metrics at Scopus". Retrieved 6 October 2019.
Scholia has an author profile for Chris Dobson.
Academic offices
Preceded by Master of St John's College, Cambridge
2007–2019 		Succeeded by
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