Chromosome instability syndrome
(Redirected from
Chromosomal breakage syndrome
)Chromosome instability syndromes are a group of inherited conditions associated with chromosomal instability and breakage. They often lead to an increased tendency to develop certain types of malignancies.[1]
The following chromosome instability syndromes are known:
- Ataxia telangiectasia
- Ataxia telangiectasia-like disorder
- Bloom syndrome
- Fanconi anaemia
- Nijmegen breakage syndrome
Neurodegenerative diseases
Chromosome instability syndromes include several inherited
Friedrich's ataxia, Huntington's disease, spinocerebellar ataxia type 1, trichothiodystrophy and xeroderma pigmentosum
.
Hypogonadism
Genes