Climbazole
topical | |
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JSmol) | |
| Chirality | Racemic mixture |
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Climbazole is a topical
eczema.[2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff.[2] Its chemical structure and properties are similar to other azole fungicides such as ketoconazole, clotrimazole and miconazole
.
Indications and formulations
It is most commonly found as an active ingredient in
OTC anti-dandruff and anti-fungal products, including shampoos, lotions and conditioners. It may be accompanied by other active ingredients such as zinc pyrithione or triclosan.[citation needed
]
Side effects
May cause localized irritation of the skin with symptoms including redness, rashes and itching.[citation needed]
References
- ^ Chemical Properties of Climbazole Archived 2007-11-13 at the Wayback Machine
- ^ PMID 11534318.