Cloflubicyne

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Cloflubicyne
Names
IUPAC name
5,6-dichloro-3,3-bis(trifluoromethyl)bicyclo[2.2.1]heptane-2,2-dicarbonitrile
Identifiers
3D model (
JSmol
)
ChemSpider
  • InChI=1S/C11H6Cl2F6N2/c12-6-4-1-5(7(6)13)9(10(14,15)16,11(17,18)19)8(4,2-20)3-21/h4-7H,1H2
    Key: NTESZNJQNKSALM-UHFFFAOYSA-N
  • C1C2C(C(C1C(C2(C#N)C#N)(C(F)(F)F)C(F)(F)F)Cl)Cl
Properties
C11H6Cl2F6N2
Molar mass 351.07 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Extremely toxic
Lethal dose or concentration (LD, LC):
0.1 mg/kg (intraperitoneal, mice)[1]
0.2 mg/kg (oral, rats)[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Cloflubicyne is a chemical compound which is a chlorinated derivative of BIDN. It is an irreversible GABA receptor antagonist with powerful convulsant effects.[3][4][5][6]

See also

References

  1. doi:10.1016/S0022-1139(00)80833-7
    .
  2. doi:10.1016/S0022-1139(00)82232-0
    .
  3. S2CID 35092380
    .
  4. S2CID 46036353
    .
  5. S2CID 27826524
    .
  6. S2CID 26207399
    .
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