Combined immunodeficiencies
Combined immunodeficiencies | |
---|---|
Other names | Combined immunity deficiency, CID |
antimicrobial prophylaxis, and Hematopoietic stem cell transplantation.[1] | |
Frequency | 1:100,000 to 1:5000 live births.[2] |
Combined immune deficiencies (CIDs) are a diverse group of inherited
Antibiotics and immunoglobulin replacement therapy are typically administered to patients as needed. Without hematopoietic cell or other transplantation aimed at correcting the underlying pathophysiological defect, prognosis is frequently poor due to T cell dysfunction.[4]
Signs and symptoms
Patients with combined immune deficiencies typically exhibit recurrent
Diagnosis
When a clinical diagnosis of combined immunodeficiency is suspected, preliminary laboratory tests should be ordered. The patient's
Treatment
Treatment for combined immunodeficiencies with defects in antibody production primarily consists of
Epidemiology
Globally, the reported incidence of CIDs ranges from 1:100,000 to 1:5000 live births; however, due to patient mortality prior to diagnosis,
References
- ^ PMC 9432339. Retrieved November 20, 2023.
- ^ . Retrieved November 20, 2023.
- ISBN 978-0-12-821028-4. Retrieved November 20, 2023.
- ^ . Retrieved November 20, 2023.
- ISSN 1058-4838. Retrieved November 20, 2023.