Compartment (pharmacokinetics)
In
fibrous tissue that enclose mammalian organs. Instead, the concept focuses on broad types of fluidic systems. This analysis is used in attempts to mathematically describe distribution of small molecules throughout organisms with multiple compartments. Various multi-compartment models can be used in the areas of pharmacokinetics and pharmacology, in the support of efforts in drug discovery, and in environmental science
.
In humans and related organisms, there are five major body compartments: the
transcellular fluids, the latter of which includes fluids in the pleural (peritoneal) cavity.[1][verification needed
] The relative percents of body mass of these are included in the following table.
Compartment | estimated % of body mass[1] |
---|---|
blood plasma | 5 |
interstitial fluid | 16 |
fat tissue | 20 (see also body fat percentage) |
intracellular fluid | 35 |
transcellular fluid | 2 |
See also
References
- ^ ISBN 0-443-07145-4. Page 102