Cornea verticillata

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Cornea verticillata
Other namesFleischer vortex[1]
Cornea verticillata: A bilateral, whorl-like corneal pattern of cream colored lines in a patient with Fabry disease.
SpecialtyOphthalmology
TreatmentDiscontinuation of the offending drug results in complete resolution of the opacity.

Cornea verticillata, also called vortex keratopathy or whorl keratopathy, is a condition characterised by

corneal deposits at the level of the basal epithelium forming a faint golden-brown whorl pattern.[2] It is seen in Fabry disease or in case of prolonged amiodarone intake.[3] Furthermore, it is a common adverse side effect of the use of rho-kinase inhibitors in glaucoma therapy.[4]

Presentation

No ocular complaints or visual difficulty is usually present.[3][5]

Pathophysiology

This keratopathy is probably a type of drug-induced lipidosis.[3]

Diagnosis

References

  1. ^ "Definition: 'Cornea Verticillata'". MediLexicon. Retrieved 29 November 2013.
  2. PMID 25677671
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  5. ^ Graff, Jordan M. (February 21, 2005). "Verticillata". University of Iowa Health Care, Ophthalmology and Visual Sciences. Retrieved 29 November 2013.