Hemoptysis

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Coughing up blood
)
Hemoptysis
Other namesHaemoptysis, coughing up of blood
epistaxis (combined with post-nasal drip
)

Hemoptysis or haemoptysis is the discharge of

trachea, or lungs. It does not necessarily involve coughing. In other words, it is the airway bleeding. This can occur with lung cancer, infections such as tuberculosis, bronchitis, or pneumonia, and certain cardiovascular conditions. Hemoptysis is considered massive at 300 mL (11 imp fl oz; 10 US fl oz). In such cases, there are always severe injuries. The primary danger comes from choking, rather than blood loss.[1]

Diagnosis

Diagnostic approach to solving the puzzle of hemoptysis.
  • Past history, history of present illness, family history[2]
    • history of tuberculosis, bronchiectasis, chronic bronchitis, mitral stenosis, etc.
    • history of
      cigarette smoking
      , occupational diseases by exposure to silica dust, etc.
  • Blood
    • duration, frequency, amount
    • Amounts of blood: large amounts of blood, or is there blood-streaked sputum
    • Probable source of bleeding: Is the blood coughed up, or vomited?
  • Bloody sputum
    • color, characters: blood-streaked, fresh blood, frothy pink, bloody gelatinous.
  • Accompanying symptoms
    • fever, chest pain, coughing, purulent sputum, mucocutaneous bleeding, jaundice.
  • Imaging examination
    • chest X-ray, CT scan and 3D reconstruction images or CT virtual bronchoscopy, bronchial angiography.
  • Laboratory tests
    • blood test: WBC
    • Sputum: cells and bacterial examinations, sputum culture
  • Bronchial fiber endoscopy[3]

Differential diagnosis

The most common causes for hemoptysis in adults are chest infections such as

Goodpasture's syndrome, and granulomatosis with polyangiitis. A rare cause of hemoptysis in women is endometriosis, which leads to intermittent hemoptysis coinciding with menstrual periods in 7% of women with thoracic endometriosis syndrome.[4] Hemoptysis may be exacerbated or even caused by overtreatment with anticoagulant drugs such as warfarin.[citation needed
]

Blood-laced mucus from the sinus or nose area can sometimes be misidentified as symptomatic of hemoptysis (such secretions can be a sign of nasal or

congestive heart failure and mitral stenosis should be ruled out. The origin of blood can be identified by observing its color. Bright-red, foamy blood comes from the respiratory tract, whereas dark-red, coffee-colored blood comes from the gastrointestinal tract. Sometimes hemoptysis may be rust-colored.[citation needed
]

Massive hemoptysis and mortality

Hemoptysis

Although there are reports that the fatality rate is as high as 80%, the mortality rate for hospitalized hemoptysis patients is 9.4% (with

n=28539), calculated from the data in the article by Kinoshita et al.[27] This is probably the most reasonable figure considering the overwhelming number of cases.[citation needed
]

The general definition of massive hemoptysis is more than 200 ml within 24 hours, but there is a wide range in the literature (100-600 ml). Considering that the total volume of the tracheal and bronchial lumen is about 150 cc,[28][29] it may be reasonable to define massive hemoptysis as 200 ml, which is a little more than 150 ml, in terms of setting the threshold for fatal hemoptysis. More than 400ml/day is not adequate for screening purposes.[citation needed]

Treatment

Treatment depends on the underlying cause. Treatments include iced

bronchial arteries can be performed to locate the bleeding, and it can often be embolized.[31] Bronchial artery embolization (BAE) is the first line treatment nowadays.[32][33][34][35][36] Surgical option is usually the last resort and can involve removal of a lung lobe or removal of the entire lung. Cough suppressants can increase the risk of choking.[1]

References

  1. ^ .
  2. ^ "Hemoptysis". The Lecturio Medical Concept Library. Retrieved 24 July 2021.
  3. .
  4. .
  5. ^ Google Health – Google
  6. ^ Google Health – Google
  7. ^ "Sarcoidosis Signs & Symptoms – Sarcoidosis – HealthCommunities.com". Archived from the original on 2009-02-21. Retrieved 2010-02-05.
  8. ^ MedlinePlus Encyclopedia: Pulmonary aspergilloma
  9. ^ Google Health – Google
  10. ^ "Histoplasmosis Symptoms – Diseases and Conditions – Mayo Clinic". Archived from the original on 2013-05-31. Retrieved 2010-02-05.
  11. ^ "Pneumonia". The Lecturio Medical Concept Library. 27 August 2020. Retrieved 1 July 2021.
  12. .
  13. .
  14. ^ "Endometriosis". The Lecturio Medical Concept Library. Retrieved 25 July 2021.
  15. ^ "Foreign Body Aspiration". The Lecturio Medical Concept Library. Retrieved 25 July 2021.
  16. ^ Pediatric Goodpasture Syndrome at eMedicine
  17. PMID 15272290
    .
  18. ^ "Granulomatosis with Polyangiitis". www.mayoclinic.org. Mayo Foundation for Medical Education and Research. Archived from the original on 22 December 2017. Retrieved 3 March 2018.
  19. ^ Adu, Emery & Madaio 2012, p. 125.
  20. ^ "What Is Churg–Strauss Syndrome?". WebMD. 30 January 2019. Retrieved 8 March 2020.
  21. ^ a b "Hemoptysis Causes – Hemoptysis – HealthCommunities.com". Archived from the original on 2009-01-23. Retrieved 2010-02-05.
  22. ^ a b c d "Other Causes of Hemoptysis – Hemoptysis – HealthCommunities.com". Archived from the original on 2009-06-08. Retrieved 2010-02-05.
  23. ^ "Mitral Stenosis". The Lecturio Medical Concept Library. Retrieved 24 July 2021.
  24. PMID 32491456
    , retrieved 2020-12-01
  25. .
  26. .
  27. ^ .
  28. .
  29. .
  30. .
  31. ^ Hanson C, Karlsson CA, Kämpe M, Lamberg K, Lindberg E, Boman LM, Stålenheim G (August 2004). Guidelines for treatment of acute lung diseases (Report). Uppsala Academic Hospital.
  32. S2CID 21597160
    .
  33. .
  34. .
  35. .
  36. .

Further reading

External links