Curling's ulcer
| Curling's ulcer | |
|---|---|
| Other names | Curling ulcer |
| Specialty | General surgery, Gastroenterology |
Curling's ulcer is an acute gastric erosion resulting as a complication from severe burns when reduced plasma volume leads to ischemia and cell necrosis (sloughing) of the gastric mucosa. The condition was first described in 1823 and named after Thomas Blizard Curling, who observed ten such patients in 1842.[1][2]
These
hemorrhage more often than other forms of intestinal ulceration[4] and had correspondingly high mortality rates (at least 80%).[1][5]
A similar condition involving elevated intracranial pressure is known as
Cushing's ulcer.[citation needed
]
Treatment
While emergency surgery was once the only treatment, combination therapies including
proton pump inhibitors such as omeprazole have made Curling's ulcer a rare complication.[6]
See also
References
- ^ PMID 5311720.
- ^ Curling, T. B. (1842). "On acute ulceration of the duodenum, in cases of burn". Medico-Chirurgical Transactions. 25: 260–281.
- PMID 5033495.
- PMID 4543410.
- ISBN 84-345-1106-1.
- PMID 2890321.