Cyclopentamine
Clinical data | |
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Other names | N,α-dimethyl-cyclopenaneethylamine |
Routes of administration | Topical (nasal spray) |
ATC code | |
Legal status | |
Legal status |
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Identifiers | |
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JSmol) | |
Chirality | Racemic mixture |
Boiling point | 171 °C (340 °F) |
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Cyclopentamine (trade names Clopane, Cyclonarol, Cyclosal, Cyklosan, Nazett, Sinos, among others) is a
vasoconstrictor. Cyclopentamine was indicated in the past as an over-the-counter (OTC) medication for use as a nasal decongestant, notably in Europe and Australia
, but has now been largely discontinued.
Pharmacology
Cyclopentamine acts as a
epinephrine (adrenaline), and dopamine.[1] Its effects on norepinephrine and epinephrine mediate its decongestant effects, while its effects on all three neurotransmitters are responsible for its stimulant properties. When ingested orally in sufficient quantities, cyclopentamine produces similar effects to amphetamine, methamphetamine, and propylhexedrine.[2][3]
Chemistry
Cyclopentamine is the cyclopentane
cyclohexyl
group.
In terms of the
alicyclic-alkylamines are weaker than unsaturated (meth)amphetamine.[citation needed
]
See also
- Amphetamine
- Cypenamine (which is trans-2-phenylcyclopentylamine)
- Methamphetamine
- Propylhexedrine (also known as cyclohexylisopropylmethylamine)
- Tranylcypromine (which is trans-2-phenylcyclopropylamine)
- Methiopropamine