Cyclopentamine

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Cyclopentamine
Clinical data
Other namesN,α-dimethyl-cyclopenaneethylamine
Routes of
administration
Topical (nasal spray)
ATC code
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • (RS)-1-Cyclopentyl-N-methylpropan-2-amine
JSmol)
ChiralityRacemic mixture
Boiling point171 °C (340 °F)
  • N(C)C(CC1CCCC1)C
  • InChI=1S/C9H19N/c1-8(10-2)7-9-5-3-4-6-9/h8-10H,3-7H2,1-2H3 checkY
  • Key:HFXKQSZZZPGLKQ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Cyclopentamine (trade names Clopane, Cyclonarol, Cyclosal, Cyklosan, Nazett, Sinos, among others) is a

vasoconstrictor. Cyclopentamine was indicated in the past as an over-the-counter (OTC) medication for use as a nasal decongestant, notably in Europe and Australia
, but has now been largely discontinued.

Pharmacology

Cyclopentamine acts as a

epinephrine (adrenaline), and dopamine.[1] Its effects on norepinephrine and epinephrine mediate its decongestant effects, while its effects on all three neurotransmitters are responsible for its stimulant properties. When ingested orally in sufficient quantities, cyclopentamine produces similar effects to amphetamine, methamphetamine, and propylhexedrine.[2][3]

Chemistry

Cyclopentamine is the cyclopentane

cyclohexyl
group.

In terms of the

alicyclic-alkylamines are weaker than unsaturated (meth)amphetamine.[citation needed
]

See also

References