D-Deprenyl
Source: Wikipedia, the free encyclopedia.
Chemical compound
Identifiers | |
---|---|
| |
JSmol) | |
| |
| |
NY (what is this?) (verify) |
d-Deprenyl, also known as or dextro-N-propargyl-N-methylamphetamine, is an MAO-B inhibitor that metabolizes into d-amphetamine and d-methamphetamine and is therefore also a norepinephrine–dopamine releasing agent.[1][2][3][4][5] It is the opposite enantiomer of l-deprenyl (selegiline).
reinforcing in scientific research, whereas l-deprenyl is not known to have any appreciable psychological reinforcement.[6][7]
In addition to its actions as an MAO-B inhibitor and NDRA, d-deprenyl has been found to bind with high
affinity to the σ1 receptor (Ki = 79 nM) similarly to various other amphetamine derivatives.[8][9] Its l-isomer, selegiline, binds with 3.5-fold lower affinity in comparison.[8][9]
See also
References
- PMID 9387872.
- PMID 23207416.
- S2CID 24859873.
- PMID 11711036.
- PMID 8473997.
- PMID 16292593.
- S2CID 10021258.
- ^ ISBN 978-0-12-376350-1.
- ^ ISBN 978-0-7484-0063-8.
|
| ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NRAs Tooltip Norepinephrine releasing agents |
| ||||||||||||||
SRAs Tooltip Serotonin releasing agents |
| ||||||||||||||
Others |
| ||||||||||||||
See also: Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins |