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Protein-coding gene in the species Homo sapiens
"HD6" redirects here. For the star, see
HD 6 .
DEFA6 Gene ontology
Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Wikidata Defensin, alpha 6 (DEFA6) also known as human alpha defensin 6 (HD6 ) is a human
Function The
nanonets that surround and entangle bacteria.
[7] Several alpha defensin genes, including DEFA6 , are clustered on chromosome 8.[3]
References Further reading
Szyk A, Wu Z, Tucker K, Yang D, Lu W, Lubkowski J (December 2006). "Crystal structures of human alpha-defensins HNP4, HD5, and HD6" . Protein Science . 15 (12): 2749–60. . Wu Z, Ericksen B, Tucker K, Lubkowski J, Lu W (September 2004). "Synthesis and characterization of human alpha-defensins 4-6". The Journal of Peptide Research . 64 (3): 118–25. . Mallow EB, Harris A, Salzman N, Russell JP, DeBerardinis RJ, Ruchelli E, Bevins CL (February 1996). "Human enteric defensins. Gene structure and developmental expression" . The Journal of Biological Chemistry . 271 (8): 4038–45. . Bevins CL, Jones DE, Dutra A, Schaffzin J, Muenke M (January 1996). "Human enteric defensin genes: chromosomal map position and a model for possible evolutionary relationships". Genomics . 31 (1): 95–106. . Eisenhauer PB, Harwig SS, Lehrer RI (September 1992). "Cryptdins: antimicrobial defensins of the murine small intestine" . Infection and Immunity . 60 (9): 3556–65. . Huttner KM, Selsted ME, Ouellette AJ (February 1994). "Structure and diversity of the murine cryptdin gene family". Genomics . 19 (3): 448–53. .
External links PDBe-KB provides an overview of all the structure information available in the PDB for Human Defensin-6
