Dalteparin sodium

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Dalteparin sodium
Clinical data
Trade namesFragmin
AHFS/Drugs.comMonograph
Pregnancy
category
Subcutaneous
ATC code
Legal status
Legal status
ECHA InfoCard
100.110.590 Edit this at Wikidata

Dalteparin is a

Factor Xa and thrombin.[3]
It is normally administered by self-injection.

The CLOT study, published in 2003, showed that in patients with malignancy and acute

unfractionated heparin in preventing blood clots.[5]

Heparins are

kidney function is reduced.[6] Approximately 70% of dalteparin is excreted through kidneys based on animal studies.[7]

In May 2019, the U.S. Food and Drug Administration (FDA) approved Fragmin injection to reduce the recurrence of symptomatic VTE in pediatric patients one month of age and older.[8] It is on the World Health Organization's List of Essential Medicines.[9]

References

  1. ^ a b "Dalteparin (Fragmin) Use During Pregnancy". Drugs.com. 27 November 2019. Retrieved 1 June 2020.
  2. ^ Dalteparin - Subcutaneous Injection, HealthLinkBC | https://www.healthlinkbc.ca/medications/fdb0271 Archived 2021-05-03 at the Wayback Machine
  3. ^ Pfizer Medical Information: Fragmin Pharmacodynamics | https://www.pfizermedicalinformation.ca/en-ca/fragmin/action-and-clinical-pharmacology# Archived 2021-05-07 at the Wayback Machine
  4. PMID 12853587
    .
  5. .
  6. .
  7. ^ Pfizer Medication Information: Fragmin Pharmacokinetics | https://www.pfizermedicalinformation.ca/en-ca/fragmin/action-and-clinical-pharmacology# Archived 2021-05-07 at the Wayback Machine
  8. ^ "FDA approves first anticoagulant (blood thinner) for pediatric patients to treat potentially life-threatening blood clots, PM FDA, May 16, 2019". U.S. Food and Drug Administration (FDA). Retrieved 17 May 2019.
  9. . WHO/MHP/HPS/EML/2021.02.

External links