Dihydroxyacetone phosphate
Names | |
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Preferred IUPAC name
3-Hydroxy-2-oxopropyl phosphate | |
Other names
Dihydroxyacetone phosphate
DHAP | |
Identifiers | |
3D model (
JSmol ) |
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ChEBI | |
ChemSpider | |
ECHA InfoCard
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100.000.280 |
KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C3H7O6P | |
Molar mass | 170.06 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dihydroxyacetone phosphate (DHAP, also glycerone phosphate in older texts) is the anion with the formula HOCH2C(O)CH2OPO32-. This anion is involved in many
Role in glycolysis
Dihydroxyacetone phosphate lies in the glycolysis metabolic pathway, and is one of the two products of breakdown of fructose 1,6-bisphosphate, along with glyceraldehyde 3-phosphate. It is rapidly and reversibly isomerised to glyceraldehyde 3-phosphate.
β-D-fructose 1,6-bisphosphate | fructose-bisphosphate aldolase | D-glyceraldehyde 3-phosphate | dihydroxyacetone phosphate | ||
+ | |||||
Compound C05378 at KEGG Pathway Database. Enzyme 4.1.2.13 at KEGG Pathway Database. Compound C00111 at KEGG Pathway Database. Compound C00118 at KEGG Pathway Database.
The numbering of the carbon atoms indicates the fate of the carbons according to their position in fructose 6-phosphate.
Dihydroxyacetone phosphate | triose phosphate isomerase
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D-glyceraldehyde 3-phosphate | |
Compound C00111 at KEGG Pathway Database.Enzyme 5.3.1.1 at KEGG Pathway Database.Compound C00118 at KEGG Pathway Database.
Click on genes, proteins and metabolites below to link to respective articles.[§ 1]
- ^ The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".
Role in other pathways
In the
DHAP is also the product of the dehydrogenation of
DHAP also has a role in the ether-lipid biosynthesis process in the protozoan parasite Leishmania mexicana.
DHAP is a precursor to 2-oxopropanal. This conversion is the basis of a potential biotechnological route to the commodity chemical
See also
- Dihydroxyacetone
- Glycerol 3-phosphate shuttle
References
- ISBN 0-7167-3051-0.
- ISBN 1-57259-153-6.
- ISBN 978-3527306732.)
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: CS1 maint: multiple names: authors list (link