Dilazep
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Trade names | Comelian Kowa |
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Dilazep is a
It is used for the treatment of
renal disorders.[3]
Synthesis
The reaction of bis-(3-hydroxypropyl)-ethylene diamine (1) with 1-Bromo-3-chloropropane (2) gives homopiperazine [19970-80-0] (3). Esterification by reaction with 3,4,5-Trimethoxybenzoyl Chloride [4521-61-3] (4) completed the synthesis of Dilazep (5).
See also
- Hexobendine, a drug with similar chemical structure
References
- PMID 9310485.
- ^ PubChem. "Dilazep". pubchem.ncbi.nlm.nih.gov. Retrieved 2021-08-18.
- ^ "Pharmaceuticals". Kowa Company Ltd.
- ^ GB1107470 idem Herbert Arnold, Kurt Pahls, Rolf Rebling,Norbert Brock, Hans-Dieter Lenke, U.S. patent 3,532,685 (1970 to Asta Werke Ag Chem Fab).
- .