Tiapamil

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Dimeditiapramine
)
Tiapamil
Clinical data
Other namesDimeditiapramine; Ro 11-1781
Identifiers
  • 2-(3,4-Dimethoxyphenyl)-2-(3-{[2-(3,4-dimethoxyphenyl)ethyl]methylamino}propyl)-1λ6,3λ6-dithiane-1,1,3,3-tetrone
JSmol)
  • CN(CCCC1(S(=O)(=O)CCCS1(=O)=O)C2=CC(=C(C=C2)OC)OC)CCC3=CC(=C(C=C3)OC)OC

Tiapamil (

INN; also known as dimeditiapramine) is a calcium antagonist or calcium channel blocker.[1][2] It is an experimental drug that has never been marketed.[3]

Tiapamil has been described as an antianginal agent. It exhibits properties of anti-arrhythmic medications. These are medications that are used to treat unusually fast or irregular heartbeats. Examples of arrhytmthic conditions include atrial fibrillation, atrial flutter, and super-ventricular tachycardia.[4] Upon research, the drug shows promising effects on treatment of these condition. Research seeks to create a treatment with tiapamil in order to mitigate the side effects of the more commonly prescribed calcium antagonist and anti-hypertensive verapamil. The two drugs have similar properties; however, tiapamil appears to treat arrhythmic conditions without many of the hypotensive, negative inotropic, and negative chronotropic side effects. Tiapamil is a calcium channel blocker that acts on the slow calcium channels. It can treat ventricular arrhythmias to a higher degree than traditional calcium antagonists.[medical citation needed]

See also

References

  1. S2CID 24609271
    .
  2. S2CID 196402596
    .
  3. ^ "Tiapamil". AdisInsight. Springer Nature Switzerland AG.
  4. S2CID 38589956
    .