Donna R. Maglott

This article relies excessively on references to primary sources. Please improve this article by adding secondary or tertiary sources. Find sources: "Donna R. Maglott" – news · newspapers · books · scholar · JSTOR (January 2023) (Learn how and when to remove this template message)

Donna R. Maglott is a staff scientist at the National Center for Biotechnology Information known for her research on large-scale genomics projects, including the mouse genome and development of databases required for genomics research.

Education and career

Maglott earned her Ph.D. in 1970 from the

While at Howard University, Maglott worked on protein synthesis during early development of sea urchins.^[5][6] At ATCC, she worked on repositories holding clone and genomic information^[7][8] and began research using genomic tools to investigate information on human chromosomes.^[9][10] In 2000, Maglott worked with Kim D. Pruitt to introduce RefSeq, a web-based resource for gene-based information that is hosted by NCBI^[11][12] and has been updated over the years.^[13][14] She has also been involved in the development of other databases at NCBI including Entrez Gene,^[15][16] ClinVar,^[17][18] STS markers, Conserved CoDing Sequences (CCDS), Map Viewer, RefSeqGene, the NIH Genetic Testing Registry (GTR), MedGen, and ClinVar.^[4] Large-scale genomics projects that Margott has worked on include the rat genome database,^[19] and the mouse genome^[20][21] and transcriptome.^[22] In 2006, Maglott was a part of the team analyzing the genome of the sea urchin, Strongylocentrotus purpuratus, which was the first genome obtained for a motile marine invertebrate.^[23][24]

Selected publications

• Mouse Genome Sequencing Consortium (2002). "Initial sequencing and comparative analysis of the mouse genome". Nature. 420 (6915): 520–562.
  PMID 12466850
  .
• Maglott, D. (2004-12-17). "Entrez Gene: gene-centered information at NCBI". Nucleic Acids Research. 33 (Database issue): D54–D58.
  PMID 15608257
  .
• Pruitt, Kim D.; Tatusova, Tatiana; Maglott, Donna R. (2007-01-01). "NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins". Nucleic Acids Research. 35 (Database issue): D61–65.
  PMID 17130148
  .
• The International Aphid Genomics Consortium (2010-02-23). Eisen, Jonathan A. (ed.). "Genome Sequence of the Pea Aphid Acyrthosiphon pisum". PLOS Biology. 8 (2): e1000313.
  PMID 20186266
  .
• Landrum, Melissa J.; Lee, Jennifer M.; Riley, George R.; Jang, Wonhee; Rubinstein, Wendy S.; Church, Deanna M.; Maglott, Donna R. (2014). "ClinVar: public archive of relationships among sequence variation and human phenotype". Nucleic Acids Research. 42 (D1): D980–D985.
  PMID 24234437
  .