Drug-induced hyperthermia
(Redirected from
Drug-induced fever
)This article relies largely or entirely on a single source. (October 2018) |
Drug-induced fever is a
pyrogen
, or damage tissues.
Triggers
- Directly caused by the drug, e.g. tumor necrosis
- Possible side effect of stimulants and entactogens (e.g. 4-MTA)
- As an adverse reaction to drugs, e.g. antibiotics or sulfa drugs.
- After drug discontinuation, e.g. heroin or fentanyl withdrawal
- Neuroleptic malignant syndrome; rare, life-threatening hyperpyrexia caused by antidopaminergic drugs (mostly antipsychotics) e.g. Haloperidol, Chlorpromazine
- triptans)
- agonists, e.g. psilocybin or LSD
- Malignant hyperthermia
Clinical treatment
The primary treatment strategy is to eliminate or discontinue the offensive agent. Supportive therapy, such as ice packs, may be provided to get the body temperature within physiologic range. In severe cases, when the fever is high enough (generally at or above ~104°F or 40°C), aggressive cooling such as an ice bath and pharmacologic therapy such as benzodiazepines may be deemed appropriate.[1]
References
- ^ Diagnosis and treatment of drug-induced hyperthermia. Musselman, ME. Saely, S. doi: 10.2146/ajhp110543 American Journal of Health-System Pharmacy January 1, 2013 vol. 70 no. 1 34-42
External links
- Tabor PA (June 1986). "Drug-induced fever". Drug Intell Clin Pharm. 20 (6): 413–20. S2CID 22448592.