Duck hepatitis B virus
Duck hepatitis B virus | |
---|---|
Virus classification | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Pararnavirae |
Phylum: | Artverviricota |
Class: | Revtraviricetes |
Order: | Blubervirales |
Family: | Hepadnaviridae |
Genus: | Avihepadnavirus |
Species: | Duck hepatitis B virus
|
Duck hepatitis B virus, abbreviated DHBV, is part of the genus Avihepadnavirus of the Hepadnaviridae, and is the causal agent of duck hepatitis B.
DHBV is a small
nucleocapsid within, is composed of the virus core antigen (DHBcAg) and surrounds the DNA genome and viral polymerase. The viral genome is a circular double stranded DNA molecule about 3000 base pairs long. The genome has three overlapping open reading frames or ORFs:[citation needed
]
- C-ORF – encoding the core antigen and pre-core protein which are processed and secreted as DHBcAg
- S-ORF – codes for the surface antigen DHBsAg
- P-ORF – encoding the viral polymerase.
On binding and
protein synthesis.[citation needed
]
Duck hepatitis B virus has provided a basis for the use of vaccines and prophylactic treatments for individuals at high risk of human