Duck hepatitis B virus

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Duck hepatitis B virus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Pararnavirae
Phylum: Artverviricota
Class: Revtraviricetes
Order: Blubervirales
Family: Hepadnaviridae
Genus: Avihepadnavirus
Species:
Duck hepatitis B virus

Duck hepatitis B virus, abbreviated DHBV, is part of the genus Avihepadnavirus of the Hepadnaviridae, and is the causal agent of duck hepatitis B.

DHBV is a small

nucleocapsid within, is composed of the virus core antigen (DHBcAg) and surrounds the DNA genome and viral polymerase. The viral genome is a circular double stranded DNA molecule about 3000 base pairs long. The genome has three overlapping open reading frames or ORFs:[citation needed
]

  • C-ORF – encoding the core antigen and pre-core protein which are processed and secreted as DHBcAg
  • S-ORF – codes for the surface antigen DHBsAg
  • P-ORF – encoding the viral polymerase.

On binding and

]

Duck hepatitis B virus has provided a basis for the use of vaccines and prophylactic treatments for individuals at high risk of human

animal model in the absence of one from the HBV,[2] and as scaffold for the development of chimeric virus-like particles.[3]

References