EAM-2201

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EAM-2201
Legal status
Legal status
Identifiers
  • (4-Ethyl-1-naphthalenyl)[1-(5-fluoropentyl)-1H-indol-3-yl]-methanone
JSmol)
  • CCC1=CC=C(C(C2=CN(CCCCCF)C3=C2C=CC=C3)=O)C4=C1C=CC=C4
  • InChI=1S/C26H26FNO/c1-2-19-14-15-23(21-11-5-4-10-20(19)21)26(29)24-18-28(17-9-3-8-16-27)25-13-7-6-12-22(24)25/h4-7,10-15,18H,2-3,8-9,16-17H2,1H3
  • Key:NSCXPXDWLZORPX-UHFFFAOYSA-N

EAM-2201 (4'-ethyl-AM-2201, 5"-fluoro-JWH-210, SGT-14) is a drug that presumably acts as a potent

synthetic cannabis smoking blends[3] Like the closely related MAM-2201 which had been first reported around a year earlier, EAM-2201 thus appears to be another novel compound invented by designer drug suppliers specifically for recreational use. Structurally, EAM-2201 is a hybrid of two known cannabinoid compounds JWH-210 and AM-2201
, both of which had previously been used as active ingredients in synthetic cannabis blends before being banned in many countries.

Pharmacology

EAM-2201 acts as a

CB2 cannabinoid receptors.[4]

Legal status

In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as EAM-2201 are

Schedule I Controlled Substances.[5]

EAM-2201 was banned in New Zealand as a

synthetic cannabis products were used as a legal alternative.[6][7]

EAM-2201 is an Anlage II controlled drug in Germany.

As of October 2015 EAM-2201 is a controlled substance in China.[8]

Detection

A forensic standard of EAM-2201 is available and commonly used in mass spectrometry.[9]

See also

References

  1. ^ Anvisa (24 July 2023). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 25 July 2023). Archived from the original on 27 August 2023. Retrieved 27 August 2023.
  2. PMID 26641707
    .
  3. PMID 23063179
    .
  4. PMID 27429655
    .
  5. ^ 21 U.S.C. § 812: Schedules of controlled substances
  6. ^ McNeilly H (1 October 2012). "I was possessed by a demon, says ex-legal high user". New Zealand Herald.
  7. ^ "Amputee: K2 'takes away my pain'". Bay of Plenty Times. New Zealand Herald. 28 November 2012.
  8. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
  9. ^ "EAM-2201". Cayman Chemical. Retrieved 21 July 2015.
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