EICAR (antiviral)
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| Other names | 5-Ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide |
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EICAR (5-Ethynyl-1-beta-D-ribofuranosylImidazole-4-CARboxamide) is a
measles virus and respiratory syncytial virus among others,[3][4][5] although it is not active against coronaviridae such as SARS-CoV-1.[6] This useful spectrum of activity means that EICAR and related derivatives continue to be investigated for the treatment of viral diseases.[7][8][9]
EICAR was originally discovered as a potent
guanylate biosynthesis pathway.[10][11] This activity is responsible for its known anticancer[10] and antiviral[12][13]
effects.