Elusys Therapeutics
| Company type | Private company |
|---|---|
| Founded | 1998 |
| Headquarters | Pine Brook, New Jersey |
Key people | Dr. Elizabeth G. Posillico (Chief Executive Officer, President and Director) |
| Website | elusys.com |
Elusys Therapeutics is a
The pathogens will be dragged to the liver where they will be destroyed.[2] The antibodies have a potential to be used for the treatments of many blood-borne diseases. Currently, the company focuses on the late-stage clinical trials of Anthim (Obiltoxaximab) to be used for treatment and prevention of inhaled anthrax.[3]
History
Ronald P. Taylor, a professor of biochemistry and molecular genetics at the University of Virginia developed protein complexes called heteropolymers that mimic the natural process of white and red blood cells in clearing out the disease off the bloodstream.
The heteropolymers have specific binding that can bind to specific pathogens on one side and red blood cells on the other side. The red blood cells with the attached pathogens are delivered to the liver to be destroyed. In animal testing, the method can clear out pathogens within 2 hours.
Taylor's research were partially funded by the
Elusys is a member of the Alliance for Biosecurity.[7] The alliance is a group of companies and scholars that work to promote the development of vaccines and other measures that can be used in the case of a pandemic or bioterrorism attack.[8][9]
Treatment
Anthim is monoclonal antibody designed for the treatment of exposure to Bacillus anthracis spores (etiologic agent of anthrax).
Elusys initially collaborated with University of Texas at Austin and United States Army Medical Research Institute of Infectious Diseases (USAMRIID) in the development of Anthim.[6] With the bioterrorism risk of anthrax, the United States Department of Health and Human Services awarded a five-year contract in 2010 valued at $143 million to develop IV-based drug to treat patients who are already infected by anthrax. In 2011, the company was awarded with an additional five-year contract valued at $68.9 million to develop intramuscular injection for anthrax prevention measure.[10] In 2012, the company was awarded additional $50.2 million to test the efficacy of the treatment.[11]
The
In November 2015, the company received a five-year contract of $44.9 million for the production and future delivery of Anthim to the Strategic National Stockpile.[14]
References
- ^ "Company Overview of Elusys Therapeutics, Inc". Bloomberg Business. Retrieved 28 November 2015.
- ^ ISSN 0161-7370. Retrieved 28 November 2015.
- ^ "Elusys Therapeutics Inc. Company Information". Hoover's. Retrieved 28 November 2015.
- ^ "Biochemist Ron Taylor Named Inventor Of The Year". University of Virginia News. 3 May 2000. Retrieved 28 November 2015.
- ^ Baard, Erik (29 August 2000). "Inventing millionaires". The Village Voice. Retrieved 28 November 2015.
- ^ PMID 12634833.
- ^ "Our Members". Alliance for Biosecurity. Retrieved 2017-02-13.[permanent dead link]
- ^ "Our Mission". Alliance for Biosecurity. Retrieved 2017-02-13.[permanent dead link]
- ^ "Our Work". Alliance for Biosecurity. Archived from the original on 2017-02-14. Retrieved 2017-02-13.
- ^ "Feds award Elusys $69 million to develop anthrax drug". NJBIZ. 12 September 2011. Retrieved 28 November 2015.
- ^ Todd, Susan (2 August 2012). "Elusys forges ahead on anthrax treatment with $50.2 million in government funding". The Star-Ledger. Retrieved 28 November 2015.
- ^ "FDA Accepts License Application For Anthrax Prevention Drug". Homeland Security Today. 1 June 2015. Retrieved 28 November 2015.[permanent dead link]
- ^ News Release (21 March 2016). "FDA approves new treatment for inhalation anthrax". FDA.
- ^ O'Brien, Kathleen (12 November 2015). "Anthrax drug wins $44.9 million contract for Morris firm". NJ.com. Retrieved 28 November 2015.