Endomorphin-2

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Endomorphin-2
Names
IUPAC name
L-Tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide
Identifiers
3D model (
JSmol
)
ChemSpider
IUPHAR/BPS
UNII
  • InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1
    Key: XIJHWXXXIMEHKW-LJWNLINESA-N
  • InChI=1/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1
    Key: XIJHWXXXIMEHKW-LJWNLINEBE
  • c1ccc(cc1)C[C@@H](C(=O)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]3CCCN3C(=O)[C@H](Cc4ccc(cc4)O)N
Properties
C32H37N5O5
Molar mass 571.667 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Endomorphin-2 (EM-2) is an

conditioned place aversion, an effect which is dynorphin A-dependent.[6] Similarly to the case of EM-1, the gene encoding for EM-2 has not yet been identified.[4][7]

See also

References

  1. ^
    ISBN 978-0-8018-6827-6
    .
  2. ISBN 978-0-7923-8757-2
    .
  3. ISBN 978-3-7643-5875-4
    .
  4. ^
    ISBN 978-3-540-38916-3
    .
  5. ISBN 978-0-306-48033-1
    .
  6. ^
    ISBN 978-0-262-26037-4
    .
  7. ISBN 978-0-470-52221-9
    .
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