Eosinophilic fasciitis

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Eosinophilic fasciitis
Other namesShulman syndrome[1]
SpecialtyRheumatology Edit this on Wikidata

Eosinophilic fasciitis (

corticosteroids, and some cases are associated with aplastic anemia.[5]

The condition was first characterized in 1974,

Raynaud's syndrome, involvement of the extremities, prominent small blood vessels (telangiectasias), and visceral changes such as swallowing problems, are absent. Nevertheless, the term remains used for diagnostic purposes.[citation needed
]

Signs and symptoms

Because the disease is rare and

joint pain and carpal tunnel syndrome.[citation needed
]

Cause

Most cases are

subcutaneous heparin,[10] may trigger the condition.[11]

Diagnosis

The key to diagnosis is the observation of skin changes in combination with eosinophilia, but the most accurate test is a biopsy of skin, fascia, and muscle.[citation needed]

Treatment

Common treatments include corticosteroids[12] such as prednisone, although medications such as hydroxychloroquine[13] have also been used. Early initiation of treatment usually portends a good prognosis if there is no

visceral involvement.[7][14]

Epidemiology

Typical age of onset is around forty to fifty years, although cases in children have been observed. It remains unclear whether the condition is more common in women or men; patient numbers are small, and studies conflict in their reports of preponderance.[15]

See also

References

  1. ^ "Eosinophilic fasciitis: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 29 October 2019.
  2. ^ "Eosinophilic". Lexico UK English Dictionary. Oxford University Press. Archived from the original on 2020-03-22. "fasciitis". Oxford Dictionaries UK English Dictionary. Oxford University Press.[dead link]
  3. ^ "Eosinophilic". Merriam-Webster.com Dictionary. Retrieved 2016-01-21. "fasciitis". Merriam-Webster.com Dictionary. Retrieved 2016-01-21.
  4. ISBN 978-1-4160-2999-1.[page needed
    ]
  5. ^ Merck Manual, Professional Edition, Eosinophilic Fasciitis
  6. ^
    PMID 1224441
    .
  7. ^
    S2CID 25791443
    .
  8. S2CID 208066832
    .
  9. S2CID 37435478
    .
  10. S2CID 30806009
    .
  11. PMID 24424187
    .
  12. S2CID 29769383
    .
  13. PMID 3232080
    .
  14. doi:10.4021/jmc118w
    .
  15. PMID 15510903
    .

Further reading

External links
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