Er blood group system

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Er blood group collection
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The Er blood group system consists of five human

antigens, Era, Erb, Er3, Er4 and Er5.[1] The incidences of Era and Er3 are each greater than 99% of the human population, while the incidence of Erb is less than 0.01%.[2][3] Er4 and Er5 are found at a high frequency in the general population.[1]

Individuals with

hemolytic disease of the fetus and newborn have been reported in women with these antibodies.[1] Expression of the Er blood group antigens is controlled by the gene PIEZO1.[1]

Era was first identified in 1982 and Erb was identified in 1988.[2] Er was recognized as a blood group collection by the International Society of Blood Transfusion in 1990[2] and promoted to a blood group in 2022.[1]

References