Etilamfetamine

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Etilamfetamine
rectal
ATC code
Legal status
Legal status
Renal
Identifiers
  • N-Ethyl-1-phenyl-propan-2-amine
JSmol)
  • N(C(Cc1ccccc1)C)CC
  • InChI=1S/C11H17N/c1-3-12-10(2)9-11-7-5-4-6-8-11/h4-8,10,12H,3,9H2,1-2H3 checkY
  • Key:YAGBSNMZQKEFCO-UHFFFAOYSA-N checkY
  (verify)

Etilamfetamine (trade names Apetinil and Adiparthrol; also known as N-ethylamphetamine) is a

appetite suppressant in the 1950s,[2] but was not as commonly used as other amphetamines such as amphetamine, methamphetamine, and benzphetamine, and was largely discontinued once newer drugs such as phenmetrazine were introduced. It most likely acts primarily as a dopamine releasing agent.[3]
Its activity as a norepinephrine or serotonin releasing agent is not known.

Chemistry

The

molecular structure of ethylamphetamine is analogous to methamphetamine, with an ethyl group in place of the methyl group.[Note 1] It can also be considered a substituted amphetamine, with an ethyl group on the amphetamine backbone.[Note 2][Note 3]

Recreational use

Ethylamphetamine can be used as a

recreational drug
and, while its prevalence is less than amphetamine's, it is still encountered as a substance taken for recreational purposes.

Ethylamphetamine produces effects similar to amphetamine and methamphetamine, though it is of weaker potency.[citation needed] At equipotent dosage, ethylamphetamine is subjectively less euphorigenic.[citation needed]

See also

References

  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  2. PMID 13389142
    .
  3. PMID 25548026
    .

Notes

  1. ^ Amphetamine is a substituted phenethylamine with a methyl group at RA position.
  2. ^ The ethyl group of ethylamphetamine is at RN position, hence the name N-ethylamphetamine.
  3. ^ Ethylamphetamine is structurally similar to N-methylamphetamine (methamphetamine), the ethyl group being replaced in methamphetamine with a methyl group.
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