Etilefrine
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Other names | (2-ethylamino-1-(3'-hydroxy-phenyl)ethanol |
AHFS/Drugs.com | International Drug Names |
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JSmol) | |
Chirality | Racemic mixture |
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Etilefrine is a
adrenoreceptors.[6]
Intravenous etilefrine increases the pulse rate, cardiac output, stroke volume,
Peripheral vascular resistance falls during the infusion of 1–8 mg etilefrine but begins to rise at higher dosage. Marked falls in pulse rate, cardiac output, stroke volume and peripheral bloodflow, accompanied by rises in mean arterial pressure, occur when etilefrine is infused after administration of intravenous propranolol 2,5 mg. These findings indicate that etilefrine has both β1 and α1 adrenergic
effects in man.
References
- PMID 5320529.
- PMID 4380206.
- ^ von Limbourg P, Just H, Lang KF (1973). "Positive inotrope Wirkung von Etilefrinhydrochlorid (EffortilR)". Kardiol. 586: 1.
- ^ Tarnow J, Brückner JB, Eberlein HG, Patschke D, Reinecke A, Schmicke P (1973). "Experimentelle Untersuchungen zur Beeinflussung der Hämodynamik in tiefer Halothannarkose durch Dopamin, Glucagon, Effortil, Noradrenalin und Dextran". Der Anaesthesist. 22: 8–15.
- ^ Carrera AL, Aguilera AM (1973). "Algunos effectos circulatorios de la m− oxifenil etanol etilmaina y sus modificaciones por el bloqueo α y β adrenergico". Arch. Inst. Cardiol. 43. Mexico: 279–287.
- PMID 4396765.
External links
- "Etilefrine". PubChem.
- "Etilefrine". Kegg.