Excitatory amino acid reuptake inhibitor
An excitatory amino acid reuptake inhibitor (EAARI) is a type of
excitatory amino acid transporters
(EAATs).
Examples of EAARIs include
EAAT2 (GLT-1).[7]
See also
- Reuptake inhibitor
- Glutamatergic
- GABA reuptake inhibitor
- Glycine reuptake inhibitor
- Excitatory amino acid receptor agonist
- Excitatory amino acid receptor antagonist
References
- ISBN 978-0-08-053257-8.
- S2CID 24207924.
- ISBN 978-3-540-87912-1.
- ^ "SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 [ Homo sapiens (human) ]". NCBI Gene. National Center for Biotechnology Information. Retrieved 11 November 2014.
Amphetamine modulates excitatory neurotransmission through endocytosis of the glutamate transporter EAAT3 in dopamine neurons. ... internalization of EAAT3 triggered by amphetamine increases glutamatergic signaling and thus contributes to the effects of amphetamine on neurotransmission.
- PMID 25033183.
- PMID 21525407.
- PMID 11325559.
In addition, RT-PCR and Western blot analysis revealed the expression of GLAST and GLT-1, astrocytic high-affinity glutamate transporters, in M5076 cells. Thus, theanine was shown to competitively inhibit the glutamate uptake by acting on these glutamate transporters.
External links
Media related to Excitatory amino acid reuptake inhibitors at Wikimedia Commons
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |