FCGR1A

Source: Wikipedia, the free encyclopedia.
FCGR1A
Available structures
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_000566

NM_010186

RefSeq (protein)

NP_034316

Location (UCSC)Chr 1: 149.78 – 149.79 MbChr 3: 96.19 – 96.2 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

High affinity immunoglobulin gamma Fc receptor I is a protein that in humans is encoded by the FCGR1A gene.[5][6][7]

Interactions

The FcgRI binds the Fc portion of IgG and causes activation of the host cell via an intercellular ITAM motif.[8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000150337 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015947 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. PMID 8697799
    .
  6. .
  7. ^ "Entrez Gene: FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)".
  8. ^ The function of Fcγ receptors in dendritic cells and macrophages Martin Guilliams Pierre Bruhns Yvan Saeys Hamida Hammad and Bart N. Lambrecht FEBRUARY 2014 | VOLUME 14 Nature Reviews Immunology

Further reading

External links


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