FOXA3

Source: Wikipedia, the free encyclopedia.
FOXA3
Available structures
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_004497

NM_008260

RefSeq (protein)

NP_004488

NP_032286

Location (UCSC)Chr 19: 45.86 – 45.87 MbChr 7: 18.75 – 18.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Hepatocyte nuclear factor 3-gamma (HNF-3G), also known as forkhead box protein A3 (FOXA3) or transcription factor 3G (TCF-3G) is a protein that in humans is encoded by the FOXA3 gene.[5][6]

Function

HNF-3G is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170608 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040891 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: forkhead box A3".
  6. PMID 9119385
    .

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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