Fenpropathrin

Source: Wikipedia, the free encyclopedia.
Fenpropathrin
Clinical data
ATC code
  • None
Identifiers
  • [Cyano-(3-phenoxyphenyl)methyl] 2,2,3,3-tetramethylcyclopropane-1-carboxylate
JSmol)
  • CC1(C(C1(C)C)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C
  • InChI=InChI=1S/C22H23NO3/c1-21(2)19(22(21,3)4)20(24)26-18(14-23)15-9-8-12-17(13-15)25-16-10-6-5-7-11-16/h5-13,18-19H,1-4H3
  • Key:XQUXKZZNEFRCAW-UHFFFAOYSA-N

Fenpropathrin, or fenopropathrin, is a widely used

synthetic pyrethroids where in they interfere with the kinetics of voltage gated sodium channels causing paralysis and death of the pest.[5] Fenpropathrin was the first of the light-stable synthetic pyrethroids to be synthesized in 1971, but it was not commercialized until 1980.[6] Like other pyrethroids with an α-cyano group, fenpropathrin also belongs to the termed type II pyrethroids (e.g. cyfluthrin, cyhalothrin, cypermethrin, deltamethrin and esfenvalerate).[7] Type II pyrethroids are a more potent toxicant than type I in depolarizing insect nerves.[8] Application rates of fenpropathrin in agriculture according to US environmental protection agency (EPA) varies by crop but is not to exceed 0.4 lb ai/acre
.

Toxicity

A person developed

organochlorines, organophosphates and pyrethroids especially at higher doses.[9][10][11][5] An acute reference dose for chronic dietary exposure for fenpropathrin is set at 0.025/mg/kg/day by US EPA. Fenpropathrin is toxic to bees if they come in contact with them directly similar to other insecticides.[12] Toxicity dissipates with time when deposited on foliage and is <24 hours
.

Environmental Fate

Fenpropathrin degrades from soil by two main mechanisms, biodegradation and photochemical degradation of surface deposits.[13] The time of degradation depends on the characteristics of the soils.[7] The half-life of disappearance for fenpropathrin in soils was 11 to 17 days under aerobic conditions and approx >1 yr under anaerobic conditions. The half-life of fenpropathrin on the surface of a sterilized sandy loam was in the range of 3 to 4 days following irradiation with natural sunlight.

Trade Names

Danitol, Meothrin, Tame.

See also

References