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Cryo-electron microscopy structure showing a peptide derived from the the SARS-CoV-2 envelope protein PDZ-binding domain (magenta) in complex with a construct containing the PDZ (blue), SH3 (yellow), and guanylate kinase-like (GK, green) domains from a host cell protein, human PALS1 (uniprot Q8N3R9). Rendered with PyMol from PDB: 7M4R​ chains A and C.

Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1

Jin Chai, Yuanheng Cai, Changxu Pang, Liguo Wang, Sean McSweeney, John Shanklin, Qun Liu

Nature Communications volume 12, Article number: 3433 (2021)

DOI: 10.1038/s41467-021-23533-x
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Author Opabinia regalis

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current02:05, 29 June 2021Thumbnail for version as of 02:05, 29 June 20211,024 × 768 (415 KB)Opabinia regalis{{Information |Description=Cryo-electron microscopy structure showing a peptide derived from the the SARS-CoV-2 envelope protein PDZ-binding domain (magenta) in complex with a construct containing the PDZ (blue), SH3 (yellow), and guanylate kinase-like (GK, green) domains from a host cell protein, human PALS1 (uniprot Q8N3R9). Rendered with PyMol from {{PDB|7M4R}} chains A and C. Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1 Jin Chai, Yuan...
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