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English: Figure 6. The molecular mechanism for the pure steroidal ERα antagonist, fulvestrant. Fulvestrant binds competitively to ERα with a high affinity. It acts as an antiestrogen chemical by reducing the half-life of ERα, resulting in a decrease in expression of ERα. Formation of the drug-receptor complex leads to stabilization of the receptor, which is degraded by an ubiquitin-proteasome complex.
Date
Source https://www.mdpi.com/1422-0067/13/11/14898
Author Adisorn Ratanaphan

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Fulvestrant

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current18:12, 2 March 2024Thumbnail for version as of 18:12, 2 March 20241,024 × 617 (184 KB)Ozzie10aaaaUploaded a work by Adisorn Ratanaphan from https://www.mdpi.com/1422-0067/13/11/14898 with UploadWizard
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