Filtration fraction
| Parameter | Value |
|---|---|
| renal blood flow | RBF = 1000 mL/min |
| hematocrit | HCT = 40% |
| glomerular filtration rate | GFR = 120 mL/min |
| renal plasma flow | RPF = 600 mL/min |
| filtration fraction | FF = 20% |
| urine flow rate | V = 1 mL/min |
| Sodium | Inulin | Creatinine | PAH |
|---|---|---|---|
SNa = 150 mEq/L
|
SIn = 1 mg/mL | SCr = 0.01 mg/mL | SPAH = |
| UNa = 710 mEq/L | UIn = 150 mg/mL | UCr = 1.25 mg/mL | UPAH = |
C Na = 5 mL/min
|
CIn = 150 mL/min | CCr = 125 mL/min | CPAH = 420 mL/min |
| ER = 90% | |||
| ERPF = 540 mL/min |
In renal physiology, the filtration fraction is the ratio of the
renal plasma flow
(RPF).
Filtration Fraction, FF = GFR/RPF, or .
The filtration fraction, therefore, represents the proportion of the fluid reaching the
renal tubules
. It is normally about 20%.
GFR on its own is the most common and important measure of
thiazide diuretics
decrease filtration fraction.
afferent and efferent arterioles, possibly through activation of alpha-1 adrenergic receptors
.
Severe
hemorrhage
will also result in an increased filtration fraction.
References
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