Frank C. Garland

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Frank C. Garland
La Jolla, San Diego, California
NationalityAmerican
Alma materJohns Hopkins University
Scientific career
FieldsEpidemiology
InstitutionsUniversity of California, San Diego

Frank Caldwell Garland (June 20, 1950 – August 17, 2010) was an American

colon cancer
.

Biography

Garland was born on June 20, 1950, in San Diego and earned a bachelor's degree in 1972 from the University of California, Los Angeles, where he majored in history.[1]

In July 1974, Garland and his brother, epidemiologist

25-hydroxy vitamin D (also known as calcidiol and 25-hydroxycholecalciferol.[1]

Garland recalled, "When my brother, Cedric, and I looked at one of the first maps produced by the National Cancer Institute of colon cancer incidence rates in the United States, we both immediately noticed a pattern, a distinct North-South gradient in incidence. This pattern changed our professional research careers. Our entire academic lives are based on that single moment."[3] While recognizing the risk of melanoma and other forms of skin cancer from excessive exposure to the Sun, the Garlands proposed that limited sun exposure would provide enough vitamin D to help prevent colon cancer, which could also be achieved by taking nutritional supplements.

Education and early career

Garland was awarded a doctorate in 1981 from Johns Hopkins University and pursued a career as an epidemiologist at the

preventive medicine
.

Published work

His later research connected deficiencies in vitamin D in residents of Northern cities with chronic disease outcomes including type 1 diabetes and higher incidence rates of breast cancer and other cancers.[1] Another of their studies which analyzed the blood from 25,000 volunteers from Washington County, Maryland found that those with the highest levels of the vitamin D metabolite calcifediol had a risk of colon cancer that was one-fifth of typical rates.[2] In a study of residents of Chicago conducted over two decades, the Garlands found that the colon cancer incidence in the quintile with the highest vitamin D intake was half that of those in the lowest quintile. Theirs was the first study to show that higher levels of vitamin D could cut rates of colon cancer.[2]

Garland co-authored two books with Frank Garland, The Calcium Connection (1988) and The Calcium Diet (1990).[4]

Personal life

A resident of San Diego, Garland died at age 60 on August 17, 2010, at

La Jolla, San Diego, California, due to cancer of the esophageal junction.[2]

References

  1. ^ a b c Fox, Margalit. "Frank C. Garland, 60, Who Connected Vitamin D Deficiency and Cancer, Dies", The New York Times, September 4, 2010.
  2. ^ a b c d Maugh II, Thomas H. "Frank C. Garland dies at 60; epidemiologist helped show importance of vitamin D: Garland and his brother Cedric were the first to demonstrate that vitamin D deficiencies play a role in cancer and other diseases.", Los Angeles Times, August 31, 2010. Accessed September 4, 2010.
  3. ^ Edwards, Kim. "Frank Garland, 1950-2010" Archived 2010-09-13 at the Wayback Machine, University of California press release dated August 24, 2010. Accessed September 4, 2010.
  4. ^ Abraham, Rachel. (1990). Book Reviews: The Calcium Diet, by Dr Cedric Garland and Dr Frank Garland. Royal Society for Public Health 110 (6): 227.