Gideon Davies

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Gideon Davies
FRS FRSC FMedSci
Gideon Davies in 2010
Born
Gideon John Davies

(1964-07-06) 6 July 1964 (age 59)[6]
Great Sutton, Cheshire
NationalityBritish
Alma materUniversity of Bristol (BSc, PhD, DSc)
ChildrenTwo daughters[6]
Awards
Scientific career
Fields
Institutions
ThesisPhosphoglycerate kinase from Bacillus stearothermophilus (1990)
Doctoral advisor
  • Herman Watson
  • Len Hall[4]
Doctoral studentsTracey Gloster[5]
Websitewww.york.ac.uk/chemistry/staff/academic/d-g/gdavies/ Edit this at Wikidata

Gideon John Davies (born 6 July 1964) FRS FRSC FMedSci is a professor of chemistry in the Structural Biology Laboratory (YSBL) at the University of York, UK.[2][7][8] Davies is best known for his ground-breaking studies into carbohydrate-active enzymes, notably analysing the conformational and mechanistic basis for catalysis and applying this for societal benefit. In 2016 Davies was appointed the Royal Society Ken Murray Research Professor at the University of York. Gideon Davies has recently been elected to the Council of the Royal Society.

Education

Davies was educated at the

Bacillus stearothermophilus, and supervised by Herman Watson and Len Hall.[4][9] He was awarded a Doctor of Science (DSc) degree from the University of Bristol in 2007.[1]

Career

Following his PhD, Davies did

postdoctoral research at the European Molecular Biology Laboratory (EMBL) outstation in Hamburg working with Keith S. Wilson on the use of synchrotron radiation in protein crystallography and also at the French National Centre for Scientific Research (CNRS) in Grenoble.[10] in 1990, Davies moved to York to work with Dale Wigley and Guy Dodson on DNA gyrase, starting his own group within YSBL in 1996 upon receiving a Royal Society University Research Fellowship.[11] He was appointed Professor at the University of York in 2001[10] and awarded a Royal Society Ken Murray Research Professorship[12] in 2016. He has collaborated with Alywn Jones, Bernard Henrissat,[13][14] Steve Withers and David Vocadlo.[3] Among those who undertook doctoral research with him are Tracey Gloster.[5]

Research

Davies research investigates the

enzymology,[18][19] glycobiology,[20][21][22][23] use as biofuels[24][25][26] and implications for gut microbiota.[27][28] His research has been funded by the Biotechnology and Biological Sciences Research Council (BBSRC),[29] European Research Council (ERC) and Alzheimer's Research UK.[10]

Davies has over 400 publications in peer-reviewed journals.[2][7][8]

Awards and honours

Davies has won a number of awards for his work. These include The

Queen's Anniversary Prize
.

Davies was elected a member of the European Molecular Biology Organization (EMBO) in 2010[10] and is a Fellow of the Royal Society of Chemistry (FRSC)

In 2010, Davies was elected a

enzyme:substrate complex govern specificity and catalysis. His research is having an immense impact on carbohydrate chemistry and biology and biological catalysis generally.[33]

Davies was elected a

Fellow of the Academy of Medical Sciences (FMedSci) in 2014, his nomination reads

Gideon Davies, who is Professor of Biological Chemistry at University of York, has made world-leading contributions to Biochemistry. He has made fundamental additions to our understanding of enzyme mechanism and carbohydrate biochemistry. As a direct result of his work into the conformation of sugars during turnover, he described the rational design of highly potent inhibitors of O-linked glucosamine modifying enzymes. These compounds are showing potential as treatments for Alzheimer's disease. Recently he has turned to study the human microbiota, which are now recognised to be an essential component of human health, and their carbohydrate metabolism is implicated in several disease states.[34]

He was awarded the John and Rita Cornforth Award of Royal Society of Chemistry in 2020

Queen's Anniversary Prize (to YSBL) in 2019[36] He was a Haworth Memorial Lectureship of Royal Society of Chemistry in 2018[37] and a Global Energy Award of Institution of Chemical Engineers winner in 2016.[38]

Personal life

Davies married Valérie Marie-Andrée Ducros[39] in 1999 (div. 2021) and has two daughters.[6]

References

  1. ^ a b Davies, Gideon John (2007). Published work submitted for the degree of D.Sc (DSc thesis). University of Bristol.
  2. ^ a b c Gideon Davies publications indexed by Google Scholar Edit this at Wikidata
  3. ^
    S2CID 205020153
    .
  4. ^ a b Professor Gideon Davies, FMedSci, FRS Biography, University of York [dead link]
  5. ^
    EThOS uk.bl.ethos.533533
    .
  6. ^
    doi:10.1093/ww/9780199540884.013.U251693. (Subscription or UK public library membership
    required.)
  7. ^ a b Gideon Davies publications indexed by the Scopus bibliographic database. (subscription required)
  8. ^ a b Gideon Davies publications from Europe PubMed Central
  9. ^ Davies, Gideon John (1990). Phosphoglycerate kinase from Bacillus stearothermophilus (PhD thesis). University of Bristol.
  10. ^ a b c d www.york.ac.uk/chemistry/staff/academic/d-g/gdavies/ Edit this at Wikidata
  11. ^ "Gideon Davies". royalsociety.org. Archived from the original on 28 June 2018. Retrieved 14 June 2017.
  12. ^ "Leading scientists awarded Royal Society Research Professorships". royalsociety.org. Retrieved 14 June 2017.
  13. PMID 9345621
    .
  14. PMID 8535779
    .
  15. PMID 25885951
    .
  16. S2CID 33800088
    .
  17. PMID 27940408
    .
  18. S2CID 205020153
    .
  19. PMID 12203498
    .
  20. PMID 12691742
    .
  21. PMID 18587388
    .
  22. PMID 26575439
    .
  23. PMID 28346405
    .
  24. PMID 26680532
    .
  25. PMID 21876164
    .
  26. PMID 26928935
    .
  27. PMID 24463512
    .
  28. PMID 25567280
    .
  29. ^ UK Government research grants awarded to Gideon Davies Archived 26 October 2014 at the Wayback Machine, via Research Councils UK
  30. ^ "Professor Paul Walton - About staff, University of York".
  31. ^ "Home". ico.chemistry.unimelb.edu.au.
  32. ^ "The GlaxoSmithKline Award".
  33. ^ "Professor Gideon John Davies FRS". London: The Royal Society. Archived from the original on 23 November 2015.
  34. ^ "Professor Gideon Davies FRS FMedSci". London: The Academy of Medical Sciences. Archived from the original on 26 October 2014.
  35. ^ "Archive".
  36. ^ "Putting proteins at the forefront of industrial biotechnology and new drug approaches".
  37. ^ "Carbohydrate Group".
  38. ^ "Global Awards - Past winners - IChemE".
  39. S2CID 8642348
    .
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