Glia maturation factor

Source: Wikipedia, the free encyclopedia.
glia maturation factor, beta
Identifiers
SymbolGMFB
Chr. 14 q22.1
Search for
StructuresSwiss-model
DomainsInterPro
glia maturation factor, gamma
Identifiers
SymbolGMFG
Chr. 19 q13.2
Search for
StructuresSwiss-model
DomainsInterPro

Glia maturation factor is a

neurotrophic factor implicated in nervous system development, angiogenesis and immune function. In humans, the glia maturation factor beta and glia maturation factor gamma proteins are encoded by the GMFB and GMFG genes
, respectively.

The structures of mouse glia maturation factors beta and gamma, solved by both crystallography and NMR, reveal similarities and critical differences with ADF-H (actin depolymerization factor homology) domains and suggest new means of experimentally addressing the function of this protein family.[1]

References

  1. ^ "Protein Summary". Archived from the original on 2011-07-21. Retrieved 2008-10-31.

See also

Stereo ribbon diagram of the crystal structure of GMFG. Spectral coloring is from blue (N-terminus) to red (C-terminus). Secondary structural elements are indicated