GRIA1
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GluR1
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Glutamate receptor 1 is a protein that in humans is encoded by the GRIA1 gene.[5][6]
Function
hippocampal formation.[7]
GRIA1 (GluR1) is centrally involved in synaptic plasticity. Expression of the GluR1 gene is significantly reduced in the human frontal cortex with increasing age.[8]
Interactions
GRIA1 has been shown to
interact
with:
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000155511 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020524 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 1652753.
- PMID 1319477.
- ^ "Entrez Gene: GRIA1 glutamate receptor, ionotropic, AMPA 1".
- S2CID 1867993.
- PMID 12933808.
- PMID 9677374.
- PMID 11567040.
- PMID 11050113.
- PMID 12573530.
Further reading
- Sun W, Ferrer-Montiel AV, Schinder AF, McPherson JP, Evans GA, Montal M (1992). "Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors". Proc. Natl. Acad. Sci. U.S.A. 89 (4): 1443–1447. PMID 1311100.
- Potier MC, Spillantini MG, Carter NP (1992). "The human glutamate receptor cDNA GluR1: cloning, sequencing, expression and localization to chromosome 5". DNA Seq. 2 (4): 211–218. PMID 1320959.
- Yakel JL, Vissavajjhala P, Derkach VA, Brickey DA, Soderling TR (1995). "Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors". Proc. Natl. Acad. Sci. U.S.A. 92 (5): 1376–1380. PMID 7877986.
- Eastwood SL, Burnet PW, Beckwith J, Kerwin RW, Harrison PJ (1994). "AMPA glutamate receptors and their flip and flop mRNAs in human hippocampus". NeuroReport. 5 (11): 1325–1328. PMID 7919190.
- Roche KW, Raymond LA, Blackstone C, Huganir RL (1994). "Transmembrane topology of the glutamate receptor subunit GluR6". J. Biol. Chem. 269 (16): 11679–11682. PMID 8163463.
- McLaughlin DP, Cheetham ME, Kerwin RW (1993). "Expression of alternatively-spliced glutamate receptors in human hippocampus". Eur. J. Pharmacol. 244 (1): 89–92. PMID 8420792.
- Roche KW, O'Brien RJ, Mammen AL, Bernhardt J, Huganir RL (1996). "Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit". Neuron. 16 (6): 1179–1188. S2CID 18608781.
- Brakeman PR, Lanahan AA, O'Brien R, Roche K, Barnes CA, Huganir RL, Worley PF (1997). "Homer: a protein that selectively binds metabotropic glutamate receptors". Nature. 386 (6622): 284–288. S2CID 4346579.
- Barria A, Derkach V, Soderling T (1998). "Identification of the Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate-type glutamate receptor". J. Biol. Chem. 272 (52): 32727–32730. PMID 9407043.
- Ripellino JA, Neve RL, Howe JR (1998). "Expression and heteromeric interactions of non-N-methyl-D-aspartate glutamate receptor subunits in the developing and adult cerebellum". Neuroscience. 82 (2): 485–497. S2CID 23219004.
- Leonard AS, Davare MA, Horne MC, Garner CC, Hell JW (1998). "SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit". J. Biol. Chem. 273 (31): 19518–19524. PMID 9677374.
- Xiao B, Tu JC, Petralia RS, Yuan JP, Doan A, Breder CD, Ruggiero A, Lanahan AA, Wenthold RJ, Worley PF (1998). "Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins". Neuron. 21 (4): 707–716. S2CID 16431031.
- Montague AA, Greer CA (1999). "Differential distribution of ionotropic glutamate receptor subunits in the rat olfactory bulb". J. Comp. Neurol. 405 (2): 233–246. S2CID 1317987.
- Leuschner WD, Hoch W (1999). "Subtype-specific assembly of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits is mediated by their n-terminal domains". J. Biol. Chem. 274 (24): 16907–16916. PMID 10358037.
- Shi SH, Hayashi Y, Petralia RS, Zaman SH, Wenthold RJ, PMID 10364548.
- Rubio ME, Wenthold RJ (1999). "Calnexin and the immunoglobulin binding protein (BiP) coimmunoprecipitate with AMPA receptors". J. Neurochem. 73 (3): 942–948. S2CID 25957729.
- Stinehelfer S, Vruwink M, Burette A (2000). "Immunolocalization of mGluR1alpha in specific populations of local circuit neurons in the cerebral cortex". Brain Res. 861 (1): 37–44. S2CID 38665483.
External links
- GRIA1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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