Glutathione S-transferase Mu 1
| GSTM1 | |||
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Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
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| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 1: 109.69 – 109.71 Mb | Chr 3: 107.89 – 107.89 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Glutathione S-transferase Mu 1 (gene name GSTM1) is a human glutathione S-transferase.
Function
.The genes encoding the mu class of enzymes are organized in a
cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.[5]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000134184 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040562 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: GSTM1 glutathione S-transferase M1".
Further reading
- Engel LS, Taioli E, Pfeiffer R, Garcia-Closas M, Marcus PM, Lan Q, et al. (July 2002). "Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review". American Journal of Epidemiology. 156 (2): 95–109. PMID 12117698.
- Navarro SL, Chang JL, Peterson S, Chen C, King IB, Schwarz Y, Li SS, Li L, Potter JD, Lampe JW (November 2009). "Modulation of human serum glutathione S-transferase A1/2 concentration by cruciferous vegetables in a controlled feeding study is influenced by GSTM1 and GSTT1 genotypes". Cancer Epidemiology, Biomarkers & Prevention. 18 (11): 2974–8. PMID 19900941.
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Glutathione S-transferase Mu 1
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