Glycine dehydrogenase

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glycine dehydrogenase
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In

enzymology, a glycine dehydrogenase (EC 1.4.1.10) is an enzyme that catalyzes the chemical reaction

glycine + H2O + NAD+ glyoxylate + NH3 + NADH + H+

The 3

.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycine:NAD+ oxidoreductase (deaminating).

This should not be confused with:

the glycine dehydrogenase (decarboxylating), which is another name for the Glycine cleavage system P-protein (EC 1.4.4.2).

or the glycine dehydroganse (cyanide forming)(EC 1.4.99.5).

or the glycine dehydrogenase (cytochrome) (EC 1.4.2.1).

References

  • GOLDMAN DS, WAGNER MJ (1962). "Enzyme systems in the mycobacteria. XIII. Glycine dehydrogenase and the glyoxylic acid cycle". Biochim. Biophys. Acta. 65 (2): 297–306.
    PMID 13948749
    .