Lumiliximab

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Gomiliximab
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Lumiliximab
Chimeric (primate/human)
TargetCD23
Clinical data
ATC code
  • none
Identifiers
CAS Number
DrugBank
ChemSpider
  • none
UNII
Chemical and physical data
FormulaC2115H3252N556O673S16
Molar mass47749.46 g·mol−1
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Lumiliximab is an IgG1k

orphan drug status and fast track designation by the FDA.[2]

It was investigated in Phase II/III

Lumiliximab was developed by IDEC Pharmaceuticals, which was acquired by Biogen. Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007.[2] Results published from the CLL clinical trial failed to meet primary endpoints.[5]

References

  1. ^ a b "International Nonproprietary Names for Pharmaceutical Substances (INN)" (PDF). WHO Drug Information. 18 (3). 2004.
  2. ^ a b "Lumiliximab". Adis Insight. Springer Nature Switzerland AG.
  3. PMID 19843887
    .
  4. ^ Clinical trial number NCT00801060 for "Evaluation of Safety and Efficacy of Fludarabine, Cyclophosphamide, and Rituximab (FCR) +/- Lumiliximab in Subjects With Previously Untreated Chronic Lymphocytic Leukemia (CLL)" at ClinicalTrials.gov
  5. S2CID 25789983
    .