Gottron's sign
Gottron's sign is a
cutaneous manifestation associated with dermatomyositis (DM), which is an inflammatory disorder affecting the skin and muscles.[1] The primary lesion of dermatomyositis appears as a violaceous, macular erythema with a symmetric distribution, which may progress and become poikilodermatous (atrophic with telangiectasia and pigmentary changes) and indurated (as a result of mucin deposition).[2]
Gottron's papules
Gottron's papules are violaceous
erythematous papules that commonly occur overlying the dorsal interphalangeal (DIP) or metacarpophalangeal joints (MCP), as well as the elbows or knee joints. They are found in approximately 70 percent of patients diagnosed with dermatomyositis.[2][3][4][5][6]
Gottron's sign
Gottron's sign are erythematous or violaceous macules or plaques overlying the elbows and/or knees and are considered to be less specific finding for DM.
Differential diagnosis
Source:[6]
| Primary dermatomyositis | Secondary dermatomyositis | Not dermatomyositis |
|---|---|---|
| Classic adult dermatomyositis | Drug induced (dtatins, NSAID, chemotherapeutics, antibiotics) | Lupus |
| Paraneoplastic dermatomyositis | Infection induced (HIV, HSV) | Lichen planus |
| Amyopathic dermatomyositis | Psoriasis | |
| Juvenile dermatomyositis | Polymorphous light eruption | |
| "overlap syndrome" dermatomyositis | Granuloma annulare | |
| Dermatitis (contact, seborrheic, atopic) | ||
| Trauma-induced knuckles |
References
- ^ "Dermatomyositis - About the Disease - Genetic and Rare Diseases Information Center". rarediseases.info.nih.gov. Retrieved 2023-12-25.
- ^ PMID 11730311.
- ^ "UpToDate". www.uptodate.com. Retrieved 2023-12-25.
- ^ "Gottron Papules: A Key Sign of an Autoimmune Muscle Disease". Verywell Health. Retrieved 2023-12-25.
- ^ a b "Adult-onset dermatomyositis | DermNet". dermnetnz.org. Retrieved 2023-12-25.
- ^ ISSN 2369-1778.
- PMID 23112358.
- PMID 23112358.