HEYL

Source: Wikipedia, the free encyclopedia.
HEYL
Identifiers
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_014571

NM_013905

RefSeq (protein)

NP_055386

NP_038933

Location (UCSC)Chr 1: 39.62 – 39.64 MbChr 4: 123.13 – 123.14 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Hairy/enhancer-of-split related with YRPW motif-like protein is a protein that in humans is encoded by the HEYL gene.[5][6][7]

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163909 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032744 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. S2CID 17342136
    .
  6. .
  7. ^ a b "Entrez Gene: HEYL hairy/enhancer-of-split related with YRPW motif-like".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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