HLX (gene)

cardiogenic mesoderm. This is followed by signals from the septum transversum that induce epithelial-mesenchymal transition in the hepatic progenitors of the gut endoderm.^[11][12] In a third stage, these signaling factors induce the liver endoderm to undergo proliferation and form liver cords. The same factor controls gut proliferation, and Hlx governs its expression. Although these mice develop anaemia, it is likely due to insufficient support from the liver in producing matrix component needed for hematopoiesis rather than an intrinsic defect in the hematopoietic cells.^[9]