HOXD9

Source: Wikipedia, the free encyclopedia.
HOXD9
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_014213

NM_013555

RefSeq (protein)

NP_055028

NP_038583

Location (UCSC)Chr 2: 176.12 – 176.12 MbChr 2: 74.53 – 74.53 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Homeobox protein Hox-D9 is a protein that in humans is encoded by the HOXD9 gene.[5][6][7]

Function

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.[7]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000128709 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043342 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. PMID 1973146
    .
  6. .
  7. ^ a b "Entrez Gene: HOXD9 homeobox D9".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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