HSF2

Source: Wikipedia, the free encyclopedia.
HSF2
Available structures
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_004506
NM_001135564
NM_001243094

NM_008297

RefSeq (protein)

NP_001129036
NP_001230023
NP_004497
NP_001230023.1

NP_032323

Location (UCSC)Chr 6: 122.4 – 122.43 MbChr 10: 57.36 – 57.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Heat shock factor protein 2 is a protein that in humans is encoded by the HSF2 gene.[5][6]

Function

HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Although the names HSF1 and HSF2 were chosen for historical reasons, these peptides should be referred to as heat-shock transcription factors.[6]

Interactions

HSF2 has been shown to

Nucleoporin 62[7] and HSF1.[8]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000025156 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019878 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. PMID 1871106
    .
  6. ^ a b "Entrez Gene: HSF2 heat shock transcription factor 2".
  7. PMID 9367915
    .
  8. .

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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